Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692462 | 1.00 | PNMT (0.44) | PNMTSLC6A2SLC6A3TAAR1SLC6A4 | |
| SCHEMBL6640956 | 1.00 | PNMT (0.44) | PNMTSLC6A2SLC6A3TAAR1SLC6A4 | |
| SCHEMBL22863972 | 0.83 | SLC6A3 (0.41) | PNMTSLC6A3 | |
| SCHEMBL6220505 | 0.81 | SLC6A3 (0.37) | PNMTSLC6A3SLC6A4 | |
| SCHEMBL3017956 | 0.81 | SLC6A3 (0.37) | PNMTSLC6A3SLC6A4 | |
| SCHEMBL3028440 | 0.81 | SLC6A3 (0.49) | PNMTSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL7489463 | 0.79 | SLC6A3 (0.47) | PNMTSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL27452976 | 0.79 | SLC6A3 (0.36) | PNMTSLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL7493476 | 0.79 | SLC6A3 (0.47) | PNMTSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL6718129 | 0.79 | SLC6A3 (0.36) | PNMTSLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486986-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486986-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486986-B2 | Microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-16 | — | — | US | disclosed |
| CN-102036990-A | Novel tyrosine kinase inhibitors | CHEMBRIDGE CORP | 2011-04-27 | — | — | CN | disclosed |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222389-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| EP-2167486-A2 | NOVEL MICROBIOCIDES | Syngeta Participations AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| CN-101679345-A | Novel microbiocides | SYNGETA PARTICIPATIONS AG | 2010-03-24 | — | — | CN | disclosed |
| WO-2008151828-A2 | NOVEL MICROBIOCIDES | SYNGETA PARTICIPATIONS AG (CH) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008151828-A2 | NOVEL MICROBIOCIDES | SYNGETA PARTICIPATIONS AG (CH) | 2008-12-18 | — | — | WO | disclosed |
| CN-1086704-C | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | AVENTIS PHARMA INC (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1148811-A | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | RHONE POULENC RORER PHARMA (US) | 1997-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222389-A1 | NOVEL MICROBIOCIDES | CD14, FPR1, MPO | PNMT 2052/4885SLC6A2 4667/4885SLC6A3 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.