Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655835 | 0.82 | KDR (0.40) | HSP90AA1P2RX7 | |
| SCHEMBL12470613 | 0.79 | HSP90AA1 (0.40) | KDM4EHSP90AA1ALDH1A1P2RX7MAPT | |
| SCHEMBL5968188 | 0.79 | ELANE (0.44) | ELANEKDM4EHSP90AA1P2RX7 | |
| SCHEMBL28022016 | 0.78 | RAB9A (0.39) | KDM4EHSP90AA1ALDH1A1P2RX7 | |
| SCHEMBL29080505 | 0.78 | HSP90AA1 (0.39) | KDM4EHSP90AA1ALDH1A1P2RX7MAPT | |
| SCHEMBL30575119 | 0.78 | HSP90AA1 (0.39) | KDM4EHSP90AA1ALDH1A1P2RX7MAPT | |
| SCHEMBL3657194 | 0.77 | HSP90AA1 (0.41) | HSP90AA1P2RX7KMT2A | |
| SCHEMBL6648327 | 0.76 | P2RX7 (0.41) | KDM4EHSP90AA1ALDH1A1P2RX7 | |
| SCHEMBL11717509 | 0.76 | ELANE (0.47) | ELANEALDH1A1 | |
| SCHEMBL8390998 | 0.76 | HSP90AA1 (0.45) | KDM4EHSP90AA1P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196614-A1 | METHODS AND COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | AXONIS THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |