SCHEMBL306238

SCHEMBL306238

CC(=O)Oc1cc2c(cc1Cl)C1(OC(=O)C3CC(CCl)=CC=C31)c1cc(Cl)c(OC(C)=O)cc1O2

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.36
LMNA P02545 3/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GLA P06280 2/20 0.34
GAA P10253 2/20 0.34
MEN1 O00255 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 2/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTT P42858 2/20 0.33
ALOX12 P18054 1/20 0.33
AKR1B1 P15121 1/20 0.32
GFER P55789 1/20 0.32
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3747895 0.84 FTO (0.35)
SCHEMBL215137 0.82 LMNA (0.35) GSTP1LMNAMAPTKDM4EGLA
SCHEMBL4575132 0.80 FTO (0.34) LMNAMAPTKDM4EGLAGAA
SCHEMBL4236674 0.72 LMNA (0.32) GSTP1LMNAMAPTKDM4EGLA
SCHEMBL2784206 0.70 FTO (0.34)
SCHEMBL15349331 0.69 GSTP1 (0.48) GSTP1LMNAMAPTKDM4EGLA
SCHEMBL29349570 0.68 MAPT (0.66) GSTP1LMNAMAPTGAAMEN1
SCHEMBL1024927 0.68 MAPT (0.66) GSTP1LMNAMAPTGAAMEN1
SCHEMBL29382186 0.66 ALDH1A1 (0.52) GSTP1LMNAMAPTKDM4EGAA
SCHEMBL20419954 0.66 ALDH1A1 (0.49) GSTP1LMNAMAPTKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993593-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING SODS AND GLIADIN BASED PEPTIDE FRAGMENTS ISOCELL S A (FR) 2015-08-26 EP disclosed
US-8092794-B2 Pharmaceutical compositions comprising SODs and prolamine based peptide fragments ISOCELL PHARMA S.A. (FR) 2012-01-10 US disclosed
US-20090226409-A1 Pharmaceutical Compositions Comprising Sods and Prolamine Based Peptide Fragments ISOCELL PHARMA S.A. (FR) 2009-09-10 US disclosed
EP-1993593-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SODS AND PROLAMINE BASED PEPTIDE FRAGMENTS Isocell Pharma S.A. (FR) 2008-11-26 EP disclosed
WO-2007105024-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SODS AND PROLAMINE BASED PEPTIDE FRAGMENTS ISOCELL PHARMA S.A. (FR) 2007-09-20 WO disclosed