Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713059 | 0.79 | GSK3B (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28486594 | 0.75 | KCNQ2 (0.40) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10474314 | 0.74 | CSNK1A1 (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28103549 | 0.74 | ADRA2A (0.69) | TAAR1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL5970012 | 0.72 | GSK3B (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL29805947 | 0.72 | CASP3 (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10685681 | 0.72 | CASP3 (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL1122916 | 0.72 | CASP3 (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28141162 | 0.71 | TBXAS1 (0.45) | KDM4EMEN1KMT2A | |
| SCHEMBL2408327 | 0.71 | KDM4E (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |