Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 7/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114036 | 0.90 | CYP11B2 (0.43) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL3063198 | 0.89 | RECQL (0.32) | CYP11B2CYP11B1RECQLPKM | |
| SCHEMBL3123674 | 0.89 | RECQL (0.32) | CYP11B2CYP11B1RECQLPKM | |
| SCHEMBL3116717 | 0.89 | RECQL (0.32) | CYP11B2CYP11B1RECQLPKM | |
| SCHEMBL1468094 | 0.89 | KDM4E (0.34) | CYP11B2CYP11B1ARRECQLPKM | |
| SCHEMBL30016435 | 0.89 | BACE1 (0.35) | CYP11B2CYP11B1RECQLPKM | |
| SCHEMBL718167 | 0.89 | BACE1 (0.35) | CYP11B2CYP11B1RECQLPKM | |
| SCHEMBL1466444 | 0.86 | RECQL (0.30) | RECQLPKM | |
| SCHEMBL1610490 | 0.86 | NISCH (0.37) | RECQLPKM | |
| SCHEMBL1862526 | 0.85 | KDM4E (0.43) | RECQLPKMNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2181100-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | CYP4X1, AADAC, CYP3A7 | CYP11B2 279/4885CYP11B1 273/4885AR 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.