Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016435 | 1.00 | BACE1 (0.35) | BACE1BACE2PGRCYP11B1CYP11B2 | |
| SCHEMBL3978545 | 0.92 | BACE1 (0.36) | BACE1BACE2PGRCYP11B1CYP11B2 | |
| SCHEMBL4751161 | 0.92 | BACE1 (0.36) | BACE1BACE2PGRCYP11B1CYP11B2 | |
| SCHEMBL3114036 | 0.92 | CYP11B2 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL1610360 | 0.89 | CYP11B1 (0.36) | BACE1BACE2PGRCYP11B1CYP11B2 | |
| SCHEMBL3121012 | 0.89 | CYP11B2 (0.39) | CYP11B1CYP11B2RECQLPKM | |
| SCHEMBL3123674 | 0.87 | RECQL (0.32) | CYP11B1CYP11B2RECQLPKMKDM4E | |
| SCHEMBL3116717 | 0.87 | RECQL (0.32) | CYP11B1CYP11B2RECQLPKMKDM4E | |
| SCHEMBL3063198 | 0.87 | RECQL (0.32) | CYP11B1CYP11B2RECQLPKMKDM4E | |
| SCHEMBL1468094 | 0.87 | KDM4E (0.34) | CYP11B1CYP11B2RECQLPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246825-B | Isoxazoline derivative containing amide structure, preparation method thereof and application of isoxazoline derivative as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-115246826-A | Quaternary ammonium salt isoxazoline compound, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-115246825-A | Isoxazoline derivative containing amide structure, preparation thereof and application of isoxazoline derivative as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-115246825-B | Isoxazoline derivative containing amide structure, preparation method thereof and application of isoxazoline derivative as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115246826-B | Quaternary ammonium salt isoxazoline compound, its preparation and application as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-115246826-A | Quaternary ammonium salt isoxazoline compound, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115246825-A | Isoxazoline derivative containing amide structure, preparation thereof and application of isoxazoline derivative as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| US-9751821-B1 | Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound and method for production of isoxazoline compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-09-05 | — | — | US | disclosed |
| US-20170233321-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| US-9676692-B2 | Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound and method for production of isoxazoline compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| US-9073910-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| US-7897630-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20100249191-A1 | N-Methyl benzamide derivatives | BAYER CROPSCIENCE SA (FR) | 2010-09-30 | — | — | US | disclosed |
| US-20100137612-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND FOR PRODUCTION OF 2- PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZLINE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2172462-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND, AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| EP-2069338-A1 | INSECTICIDAL ISOXAZOLINES | Bayer CropScience AG (DE) | 2009-06-17 | — | — | EP | disclosed |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-05-28 | — | — | US | disclosed |
| EP-1966195-A2 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008019760-A1 | INSECTICIDAL ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007075459-A2 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137612-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND FOR PRODUCTION OF 2- PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZLINE COMPOUND | ADH1C, CYP2E1, ADH1A | BACE1 1023/4885BACE2 1395/4885PGR 2604/4885 |
| US-20100249191-A1 | N-Methyl benzamide derivatives | GNMT, SCN1A, INA | BACE1 4066/4885BACE2 3251/4885PGR 4774/4885 |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | PRXL2A, C5, CBR3 | BACE1 3993/4885BACE2 3139/4885PGR 2877/4885 |
| US-20170233321-A1 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND | ADH1C, ADH1A, CYP2E1 | BACE1 1224/4885BACE2 1775/4885PGR 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.