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Tmpyp4

Tmpyp4

SCHEMBL30632001

C[n+]1ccc(-c2c3nc(c(-c4cc[n+](C)cc4)c4ccc([nH]4)c(-c4cc[n+](C)cc4)c4nc(c(-c5cc[n+](C)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1.Cc1ccc(S(=O)(=O)[O-])cc1.Cc1ccc(S(=O)(=O)[O-])cc1.Cc1ccc(S(=O)(=O)[O-])cc1.Cc1ccc(S(=O)(=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Tmpyp4. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 1.00
▸ ENPP2 Q13822 1/20 0.52
▸ TOP1 P11387 4/20 0.42
▸ CYCS P99999 3/20 0.41
▸ ABCG2 Q9UNQ0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tmpyp4 SCHEMBL8153900 1.00 TERT (1.00) TERTENPP2TOP1CYCSABCG2
Tmpyp4 SCHEMBL6045450 0.99 TERT (0.98) TERTENPP2TOP1CYCSABCG2
Tmpyp4 SCHEMBL3792658 0.89 TERT (0.80) TERTENPP2TOP1CYCSABCG2
Tmpyp4 SCHEMBL7112191 0.89 TERT (0.80) TERTENPP2TOP1CYCSABCG2
SCHEMBL18016429 0.87 TERT (0.82) TERTENPP2TOP1CYCSABCG2
SCHEMBL3461640 0.86 TERT (0.73) TERTENPP2TOP1CYCSABCG2
SCHEMBL9267975 0.84 TERT (0.71) TERTENPP2TOP1CYCSABCG2
Hydrochloric Acid SCHEMBL30368468 0.83 TERT (0.70) TERTENPP2TOP1CYCSABCG2
Hydrochloric Acid SCHEMBL2429143 0.83 TERT (0.70) TERTENPP2TOP1CYCSABCG2
Tmpyp4 SCHEMBL265519 0.83 TERT (0.97) TERTENPP2TOP1CYCSABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4385499-A1 A METHOD TO ENABLE NANOPARTICLES STORED WITH A SPECIFIC TYPE OF ASSEMBLY TO MAINTAIN THIS TYPE OF ASSEMBLY UPON RECONSTITUTION Nanobacterie (FR) 2024-06-19 — — EP claimed
EP-4371574-A1 IRON OXIDE NANOPARTICLES COMPRISING TWO CENTERS OF ACTIVITIES OR FREE RADICAL CAPTURE/PRODUCTION FOR AN ENHANCED ACTIVITY Nanobacterie (FR) 2024-05-22 — — EP claimed
US-20240076654-A1 AUTOMATED METHODS FOR SCALABLE, PARALLELIZED ENZYMATIC BIOPOLYMER SYNTHESIS AND MODIFICATION USING MICROFLUIDIC DEVICES U.S. DEPARTMENT OF ENERGY 2024-03-07 — — US disclosed
US-11851651-B2 Automated methods for scalable, parallelized enzymatic biopolymer synthesis and modification using microfluidic devices MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-12-26 — — US disclosed
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