Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.68 |
| ▸ | TOP1 | P11387 | 4/20 | 0.55 |
| ▸ | CYCS | P99999 | 3/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30368468 | 1.00 | TERT (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL9267975 | 0.98 | TERT (0.71) | TERTENPP2TOP1CYCSABCG2 | |
| Zinc Ion SCHEMBL11569891 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL2334465 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL8994427 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL23706379 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL5051415 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL6139711 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL498417 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 | |
| SCHEMBL2334489 | 0.95 | ENPP2 (0.70) | TERTENPP2TOP1CYCSABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753551-B2 | Stable organic light emitting coating | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. | 2023-09-12 | — | — | US | disclosed |
| US-11635547-B2 | Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive | ESSILOR INTERNATIONAL (FR) | 2023-04-25 | — | — | US | disclosed |
| EP-3497488-B2 | OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2023-03-22 | — | — | EP | disclosed |
| US-11327202-B2 | Composition for the manufacture of an ophthalmic lens comprising an encapsulated light-absorbing additive | ESSILOR INTERNATIONAL (FR) | 2022-05-10 | — | — | US | disclosed |
| US-11204445-B2 | Ophthalmic lens comprising an encapsulated light-absorbing additive | ESSILOR INTERNATIONAL (FR) | 2021-12-21 | — | — | US | disclosed |
| US-20210315822-A1 | BIOMIMETIC REBUILDING OF MULTIFUNCTIONAL RED BLOOD CELLS | UNM RAINFOREST INNOVATIONS | 2021-10-14 | — | — | US | disclosed |
| US-20210071014-A1 | STABLE ORGANIC LIGHT EMITTING COATING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2021-03-11 | — | — | US | disclosed |
| US-20200386913-A1 | Composition for the Manufacture of an Ophthalmic Lens Comprising an Encapsulated Light-Absorbing Additive | ESSILOR INTERNATIONAL (FR) | 2020-12-10 | — | — | US | disclosed |
| EP-3495853-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2020-07-29 | — | — | EP | disclosed |
| EP-3497488-B1 | OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2020-06-17 | — | — | EP | disclosed |
| US-10253251-B2 | Nanomatrix separation of chromophores and uses thereof in luminescent devices | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-04-09 | — | — | US | disclosed |
| US-10108027-B2 | Method of determining the configuration of an ophthalmic filter | ESSILOR INTERNATIONAL (FR) | 2018-10-23 | — | — | US | disclosed |
| EP-3282290-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN ENCAPSULATED LIGHT-ABSORBING ADDITIVE | ESSILOR INT (FR) | 2018-10-17 | — | — | EP | disclosed |
| US-9073937-B2 | Organic photovoltaic-battery hybrid device | BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2015-07-07 | — | — | US | disclosed |
| US-20150079423-A1 | NANOMATRIX SEPARATION OF CHROMOPHORES AND USES THEREOF IN LUMINESCENT DEVICES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2015-03-19 | — | — | US | disclosed |
| US-20150002809-A1 | OPHTHALMIC FILTER | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2015-01-01 | — | — | US | disclosed |
| US-8917018-B2 | Nanomatrix separation of chromophores and uses thereof in luminescent devices | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2014-12-23 | — | — | US | disclosed |
| US-20140320806-A1 | METHOD OF DETERMINING THE CONFIGURATION OF AN OPHTHALMIC FILTER | UNIVERSITE PARIS 6 PIERRE ET MARIE CURIE (FR) | 2014-10-30 | — | — | US | disclosed |
| US-20120318348-A1 | ORGANIC PHOTOVOLTAIC-BATTERY HYBRID DEVICE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2012-12-20 | — | — | US | disclosed |
| US-20110215716-A1 | NANOMATRIX SEPARATION OF CHROMOPHORES AND USES THEREOF IN LUMINESCENT DEVICES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120318348-A1 | ORGANIC PHOTOVOLTAIC-BATTERY HYBRID DEVICE | GJB2, GJA1, VCL | TERT 970/4885ENPP2 4316/4885TOP1 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.