Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632385 | 0.83 | AADAT (0.60) | AADATKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL6989831 | 0.77 | ALDH1A1 (0.64) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7448478 | 0.74 | ALDH1A1 (0.67) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7448471 | 0.74 | ALDH1A1 (0.67) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6988577 | 0.72 | ALDH1A1 (0.61) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11619526 | 0.72 | ALDH1A1 (0.72) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL30632335 | 0.71 | KDM4E (0.56) | KMT2AMEN1ALDH1A1NPSR1MAPT | |
| SCHEMBL6999720 | 0.71 | ALDH1A1 (0.60) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL394112 | 0.71 | MEN1 (0.62) | AADATKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL394111 | 0.71 | MEN1 (0.62) | AADATKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024327-A | Isoindolinone-based derivative, and preparation method and application thereof | 华东理工大学 | 2023-11-10 | — | — | CN | disclosed |