Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270563 | 0.86 | ALDH1A1 (0.77) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL29459253 | 0.86 | ALDH1A1 (0.77) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL7840770 | 0.86 | ALDH1A1 (0.77) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL28661085 | 0.86 | ALDH1A1 (0.77) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL29459410 | 0.86 | ALDH1A1 (0.77) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL30632346 | 0.83 | AADAT (0.52) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL21914462 | 0.76 | AADAT (0.59) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL9417615 | 0.75 | ALDH1A1 (0.72) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL21851969 | 0.75 | AADAT (1.00) | AADATALDH1A1GAAKMT2APOLB | |
| SCHEMBL478614 | 0.74 | ALDH1A1 (1.00) | AADATALDH1A1GAAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024327-A | Isoindolinone-based derivative, and preparation method and application thereof | 华东理工大学 | 2023-11-10 | — | — | CN | disclosed |