Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633678 | 1.00 | L3MBTL1 (0.47) | L3MBTL1EPHX1ALDH1A1KDM4ETSHR | |
| SCHEMBL24011439 | 0.91 | EPHX1 (0.50) | L3MBTL1EPHX1ALDH1A1KDM4ETSHR | |
| SCHEMBL30306690 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRSMN1; SMN2GAA | |
| SCHEMBL26633732 | 0.79 | RAB9A (0.53) | EPHX1ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL26764484 | 0.78 | KMT2A (0.51) | L3MBTL1EPHX1ALDH1A1KDM4ETSHR | |
| SCHEMBL26633749 | 0.78 | EPHX1 (0.43) | EPHX1MEN1HPGDKMT2A | |
| SCHEMBL30634168 | 0.75 | LMNA (0.53) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL30288085 | 0.75 | LMNA (0.53) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL26633838 | 0.75 | LMNA (0.53) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL26633844 | 0.75 | LMNA (0.53) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | L3MBTL1 3643/4885EPHX1 3913/4885ALDH1A1 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.