Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27957250 | 0.84 | POLB (0.56) | DHODHL3MBTL1RAB9ATSHRCASP3 | |
| SCHEMBL30747808 | 0.82 | TSHR (0.58) | L3MBTL1RAB9ATSHRPOLBALDH1A1 | |
| SCHEMBL27957258 | 0.78 | ALDH1A1 (0.47) | L3MBTL1TSHRPOLBALDH1A1TDP1 | |
| SCHEMBL22492342 | 0.77 | PLA2G2A (0.54) | DHODHPLA2G2AL3MBTL1KDM4ELMNA | |
| SCHEMBL7372413 | 0.76 | LMNA (0.60) | DHODHALDH1A1KDM4EGAALMNA | |
| SCHEMBL522838 | 0.76 | ALDH1A1 (0.57) | DHODHL3MBTL1RAB9ATSHRPOLB | |
| SCHEMBL6133440 | 0.75 | FFAR4 (0.58) | L3MBTL1RAB9ATSHRPOLBALDH1A1 | |
| SCHEMBL31371501 | 0.75 | FFAR4 (0.58) | L3MBTL1RAB9ATSHRPOLBALDH1A1 | |
| SCHEMBL1646547 | 0.75 | HTT (0.57) | L3MBTL1POLBALDH1A1TDP1KDM4E | |
| SCHEMBL21007975 | 0.74 | TDP1 (0.67) | DHODHL3MBTL1RAB9ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |