Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.38 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954400 | 1.00 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29952900 | 0.84 | HTR3E (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13334901 | 0.80 | TP53 (0.30) | — | |
| SCHEMBL10232889 | 0.78 | MPL (0.37) | — | |
| SCHEMBL10232830 | 0.76 | NOTUM (0.39) | IDO1NOTUMLMNA | |
| SCHEMBL10232891 | 0.76 | ALKBH5 (0.37) | NOTUM | |
| SCHEMBL29958052 | 0.73 | KIF11 (0.44) | — | |
| SCHEMBL2916024 | 0.73 | AHR (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29952346 | 0.72 | RAPGEF4 (0.34) | RAPGEF4 | |
| SCHEMBL997705 | 0.72 | RAPGEF4 (0.34) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105936-B | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-117105936-A | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2023-11-24 | — | — | CN | disclosed |