Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NMT1 | P30419 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NMT2 | O60551 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31510476 | 1.00 | PTGS2 (0.53) | PTGS2MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2544566 | 0.85 | LMNA (0.68) | MAPTLMNAALDH1A1HPGDNMT1 | |
| SCHEMBL621513 | 0.83 | MAPT (0.57) | PTGS2MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL32684711 | 0.83 | LMNA (0.69) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL619012 | 0.82 | MAPT (0.56) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL619241 | 0.82 | NMT1 (0.58) | PTGS2MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL30747808 | 0.81 | TSHR (0.58) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL11655288 | 0.80 | KDM4E (0.59) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL29523397 | 0.80 | NUDT1 (0.57) | MAPTLMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1768671 | 0.80 | NUDT1 (0.57) | MAPTLMNAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543878-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | Astrazeneca AB (SE) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247489-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2023-12-28 | — | — | WO | disclosed |