Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768671 | 1.00 | NUDT1 (0.57) | NUDT1TSHRMEN1KMT2APKM | |
| SCHEMBL5669102 | 0.89 | TSHR (0.54) | NUDT1TSHRMEN1KMT2APKM | |
| SCHEMBL29259654 | 0.86 | ALDH1A1 (0.51) | NUDT1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL30313610 | 0.85 | TSHR (0.60) | TSHRALDH1A1RXFP1LMNACYP3A4 | |
| SCHEMBL27605541 | 0.85 | KMT2A (0.44) | NUDT1TSHRMEN1KMT2APKM | |
| SCHEMBL30201809 | 0.84 | LMNA (0.50) | NUDT1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL13610182 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1RXFP1LMNACYP3A4 | |
| SCHEMBL31083564 | 0.83 | SLC22A12 (0.51) | NUDT1TSHRMEN1KMT2APKM | |
| SCHEMBL26649707 | 0.82 | KMT2A (0.43) | NUDT1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL827693 | 0.82 | PSMD14 (0.57) | MEN1KMT2APKMALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423757-A | Tricyclic heteroaryl compounds useful as IRAK4 inhibitors | 百时美施贵宝公司 | 2022-04-29 | — | — | CN | disclosed |