SCHEMBL3064787

SCHEMBL3064787

CCOC(=O)CC(O)CO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
ALDH1A1 P00352 6/20 0.44
TRPA1 O75762 1/20 0.44
LMNA P02545 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
DUSP3 P51452 1/20 0.43
MEN1 O00255 1/20 0.43
ALOX15 P16050 3/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 2/20 0.40
CHRM1 P11229 1/20 0.40
ADORA1 P30542 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3064783 1.00 MGAM (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1895727 1.00 MGAM (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1258369 0.88 GAA (0.55) MGAMGAASIMGAM2ALDH1A1
Glycerin SCHEMBL28329026 0.85 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL1427228 0.84 MGAM (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL9743315 0.84 MGAM (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL3853840 0.84 MGAM (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL7194339 0.83 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL5453913 0.82 MGAM (0.48) MGAMGAASIMGAM2ALDH1A1
SCHEMBL27749970 0.81 LMNA (0.38) ALDH1A1LMNAKMT2AKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104673478-A Tea-seed oil processing technique UNIV GUANGXI 2015-06-03 CN claimed
US-20100261251-A1 MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-10-14 US claimed
EP-2179050-A1 MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE Agency for Science, Technology And Research (SG) 2010-04-28 EP claimed
WO-2009008834-A1 MICROBIAL KINETIC RESOLUTION OF ETHYL-3,4-EPOXYBUTYRATE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-01-15 WO claimed
JP-2007506661-A 2007-03-22 JP claimed
US-20070037846-A1 Pyrazolidinedione derivatives ACTELION PHARMACEUTICALS, LTD. (CH) 2007-02-15 US claimed
EP-1638540-A2 PYRAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS PLATELET AGGREGATION INHIBITORS Actelion Pharmaceuticals Ltd. (CH) 2006-03-29 EP claimed
WO-2005000281-A2 PYRAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS PLATELET AGGREGATION INHIBITORS ACTELION PHARMACEUTICALS LTD. (CH) 2005-01-06 WO claimed
CN-119529588-A Environment-friendly material for repairing pavement inspection well seat and use method 北京盛安筑达科技有限公司 2025-02-28 CN disclosed
CN-116904530-A Biological preparation method of atorvastatin calcium intermediate 江苏福瑞康泰药业有限公司 2023-10-20 CN disclosed
CN-115894290-A Preparation method of atorvastatin calcium intermediate (R) - (-) -4-cyano-3-hydroxy ethyl butyrate 宿迁阿尔法科技有限公司 2023-04-04 CN disclosed
WO-2020157491-A1 G-A CROSSLINKING CYTOTOXIC AGENTS FEMTOGENIX LIMITED (GB) 2020-08-06 WO disclosed
CN-109688813-A Flying pest attractant 理研香料控股株式会社 2019-04-26 CN disclosed
CN-109310085-A Flying pest attractant 理研香料控股株式会社 2019-02-05 CN disclosed
US-6608214-B2 Hydrogenating optically active 4-substituted oxy-3-hydroxy-butyrate followed by simultaneous deprotection and ring closure; economic and efficient synthesis TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-08-19 US disclosed
US-20030105341-A1 Process for producing optically active gamma-butyrolactone TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-06-05 US disclosed
EP-1277748-A1 Process for producing optically active y-Butyrolactone Takasago International Corporation (JP) 2003-01-22 EP disclosed
US-6331553-B1 INHIBITORS OF NITRIC OXIDE SYNTHASE; TREATING CEREBROVASCULAR DISEASES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2001-12-18 US disclosed
CN-1240419-A Aromatic amine derivatives having NOS inhibitory effect CHUGAI PHARMACEUTICAL CO LTD (JP) 2000-01-05 CN disclosed
EP-0949242-A1 AROMATIC AMINE DERIVATIVES HAVING NOS INHIBITORY EFFECT Chugai Seiyaku Kabushiki Kaisha (JP) 1999-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037846-A1 Pyrazolidinedione derivatives P2RY1, P2RY4, P2RY2 MGAM 4610/4885GAA 3492/4885SI 3878/4885
US-20030105341-A1 Process for producing optically active gamma-butyrolactone HSD17B10, HSD17B1, HSD17B12 MGAM 880/4885GAA 1376/4885SI 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.