Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070514 | 0.86 | TDP1 (0.51) | KMT2ASMN1; SMN2 | |
| SCHEMBL4520513 | 0.83 | LMNA (0.53) | KMT2ASMN1; SMN2 | |
| SCHEMBL29505934 | 0.82 | KMT2A (0.75) | KMT2ANR1H4NR4A2PLA2G4BRXRA | |
| SCHEMBL1333545 | 0.82 | KMT2A (0.75) | KMT2ANR1H4NR4A2PLA2G4BRXRA | |
| SCHEMBL29505938 | 0.82 | KMT2A (0.75) | KMT2ANR1H4NR4A2PLA2G4BRXRA | |
| SCHEMBL6297991 | 0.82 | MAPK1 (0.46) | TP53SMN1; SMN2 | |
| SCHEMBL2983617 | 0.81 | PLA2G4B (0.57) | NR1H4PLA2G4BRXRARXRBTP53 | |
| SCHEMBL931583 | 0.81 | NR1H4 (0.75) | KMT2ANR1H4NR4A2MRGPRX4NR4A1 | |
| Hydrochloric Acid SCHEMBL30608606 | 0.81 | KMT2A (0.73) | KMT2ANR1H4NR4A2PLA2G4BRXRA | |
| SCHEMBL8417231 | 0.81 | KMT2A (0.63) | KMT2ANR1H4NR4A2PLA2G4BNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848380-A1 | LABELLED NUCLEOTIDES | Illumina Cambridge Limited (GB) | 2021-07-14 | — | — | EP | disclosed |
| US-11028115-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11028116-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11008359-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-18 | — | — | US | disclosed |
| US-10995111-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-04 | — | — | US | disclosed |
| US-20210047357-A1 | LABELLED NUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| EP-3438116-B1 | LABELLED NUCLEOTIDES | ILLUMINA CAMBRIDGE LTD (GB) | 2021-02-17 | — | — | EP | disclosed |
| US-20210009623-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2021-01-14 | — | — | US | disclosed |
| US-20210009622-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2021-01-14 | — | — | US | disclosed |
| US-20200325167-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2020-10-15 | — | — | US | disclosed |
| US-8084590-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2011-12-27 | — | — | US | disclosed |
| US-20100311178-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED | 2010-12-09 | — | — | US | disclosed |
| US-7795424-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-09-14 | — | — | US | disclosed |
| EP-2119722-A1 | Labelled nucleotides | Illumina Cambridge Limited (GB) | 2009-11-18 | — | — | EP | disclosed |
| EP-1560838-B1 | LABELLED NUCLEOTIDES | ILLUMINA CAMBRIDGE LTD (GB) | 2009-05-13 | — | — | EP | disclosed |
| US-20090062145-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2006-07-20 | — | — | US | disclosed |
| EP-1560838-A1 | LABELLED NUCLEOTIDES | Solexa Limited (GB) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004018493-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325167-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | RNGTT, DNTT, POLQ | KMT2A 1529/4885NR1H4 4747/4885NR4A2 3822/4885 |
| US-20210009623-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-20210009622-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-11008359-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-20100311178-A1 | Labelled nucleotides | NUDT1, DUT, NT5C2 | KMT2A 2394/4885NR1H4 2259/4885NR4A2 4148/4885 |
| US-20210047357-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-10995111-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-11028116-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
| US-11028115-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | KMT2A 2436/4885NR1H4 2226/4885NR4A2 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.