Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18685480 | 0.86 | TDP1 (0.49) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL930302 | 0.86 | NR1H4 (0.54) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL3065476 | 0.86 | KMT2A (0.61) | KMT2ASMN1; SMN2 | |
| SCHEMBL1989713 | 0.84 | KMT2A (0.62) | TDP1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL5665404 | 0.83 | SMN1; SMN2 (0.55) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL24141585 | 0.82 | ADRB2 (0.49) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL13635033 | 0.81 | TDP1 (0.44) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL4520513 | 0.81 | LMNA (0.53) | TDP1L3MBTL1KMT2AMAPTNPC1 | |
| SCHEMBL8703734 | 0.81 | ADRB2 (0.49) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL7095551 | 0.80 | ADRB2 (0.56) | TDP1L3MBTL1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848380-A1 | LABELLED NUCLEOTIDES | Illumina Cambridge Limited (GB) | 2021-07-14 | — | — | EP | disclosed |
| EP-3848380-A1 | LABELLED NUCLEOTIDES | Illumina Cambridge Limited (GB) | 2021-07-14 | — | — | EP | disclosed |
| US-11028115-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11028116-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11028116-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11028115-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11008359-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-18 | — | — | US | disclosed |
| US-11008359-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-18 | — | — | US | disclosed |
| US-10995111-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-04 | — | — | US | disclosed |
| US-10995111-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-04 | — | — | US | disclosed |
| EP-1560838-B1 | LABELLED NUCLEOTIDES | ILLUMINA CAMBRIDGE LTD (GB) | 2009-05-13 | — | — | EP | disclosed |
| US-20090062145-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-20090062145-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-20090062145-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2006-07-20 | — | — | US | disclosed |
| EP-1560838-A1 | LABELLED NUCLEOTIDES | Solexa Limited (GB) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004018493-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | RNGTT, DNTT, POLQ | TDP1 536/4885L3MBTL1 1287/4885ADRB2 4882/4885 |
| US-11008359-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TDP1 546/4885L3MBTL1 1632/4885ADRB2 4345/4885 |
| US-10995111-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TDP1 546/4885L3MBTL1 1632/4885ADRB2 4345/4885 |
| US-11028116-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TDP1 546/4885L3MBTL1 1632/4885ADRB2 4345/4885 |
| US-11028115-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TDP1 546/4885L3MBTL1 1632/4885ADRB2 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.