SCHEMBL30656102

SCHEMBL30656102

Cc1ncc(COc2ccc3sc(C)c(C(=O)NC4(CO)CCOCC4)c3c2)s1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 2/20 0.38
MMP7 P09237 2/20 0.38
ADAMTS4 O75173 1/20 0.38
ADAM17 P78536 1/20 0.38
ADAMTS1 Q9UHI8 1/20 0.38
ADAMTS5 Q9UNA0 1/20 0.38
BTK Q06187 1/20 0.37
MMP2 P08253 1/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
DGAT2 Q96PD7 4/20 0.34
CD274 Q9NZQ7 1/20 0.34
CNR2 P34972 2/20 0.33
CNR1 P21554 1/20 0.33
ANO1 Q5XXA6 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
GSK3B P49841 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656263 0.95 L3MBTL1 (0.34) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656104 0.93 ABL1 (0.36) ADAM17BTKCD274CNR2CNR1
SCHEMBL30656220 0.92 L3MBTL1 (0.33) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656207 0.87 CNR2 (0.38) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656232 0.86 KDM4E (0.43) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL24485705 0.85 GAA (0.42) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL29629850 0.85 GAA (0.42) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656018 0.85 ADAM17 (0.38) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656223 0.85 BTK (0.42) MMP3MMP7ADAMTS4ADAM17ADAMTS1
SCHEMBL30656261 0.84 CNR2 (0.34) MMP3MMP7ADAMTS4ADAM17ADAMTS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed