SCHEMBL30656261

SCHEMBL30656261

Cc1ncc(COc2ccc3sc(C)c(C(=O)NC4(C(N)=O)CCOC4)c3c2)s1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
GSK3B P49841 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
ADAMTS4 O75173 1/20 0.30
MMP3 P08254 1/20 0.30
MMP7 P09237 1/20 0.30
ADAM17 P78536 1/20 0.30
ADAMTS1 Q9UHI8 1/20 0.30
ADAMTS5 Q9UNA0 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656207 0.95 CNR2 (0.38) CNR2CYP4F2CYP4A11L3MBTL1ADAMTS4
SCHEMBL30656075 0.93 L3MBTL1 (0.32) CNR2L3MBTL1
SCHEMBL30656155 0.91 CCNE1 (0.32) CYP4F2CYP4A11CCNE1CDK2GSK3B
SCHEMBL24485426 0.86 GAA (0.42) L3MBTL1
SCHEMBL29629720 0.86 GAA (0.42) L3MBTL1
SCHEMBL30656102 0.84 MMP3 (0.38) CNR2CCNE1CDK2GSK3BL3MBTL1
SCHEMBL30656220 0.83 L3MBTL1 (0.33) CNR2L3MBTL1ADAMTS4MMP3MMP7
SCHEMBL30656263 0.82 L3MBTL1 (0.34) CNR2L3MBTL1ADAMTS4MMP3MMP7
SCHEMBL24485415 0.82 GAA (0.41) L3MBTL1
SCHEMBL29629905 0.82 GAA (0.41) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed