SCHEMBL30656120

SCHEMBL30656120

Cc1sc2ccc(OCc3cccnc3C(F)(F)F)cc2c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC26A4 O43511 3/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PPARD Q03181 3/20 0.39
PPARA Q07869 3/20 0.39
EDNRA P25101 1/20 0.38
PPARG P37231 1/20 0.37
ANO1 Q5XXA6 3/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
CD38 P28907 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
OPRL1 P41146 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
PTGER4 P35408 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31350334 0.91 CD38 (0.42) SLC26A4MEN1KMT2APPARDPPARA
SCHEMBL30656331 0.89 ALDH1A1 (0.38) SLC26A4MEN1KMT2APPARDPPARA
SCHEMBL30656197 0.85 SCN9A (0.35) SLC26A4PPARDPPARAPPARGCD38
SCHEMBL30655957 0.85 CD38 (0.38) SLC26A4MEN1KMT2APPARDPPARA
SCHEMBL30656093 0.84 ALOX5 (0.39) KMT2AMRGPRX4CD38POLBLMNA
SCHEMBL30656226 0.84 CD38 (0.37) EDNRACD38OPRL1MAOAMAOB
SCHEMBL30656258 0.84 CD38 (0.37) EDNRACD38OPRL1MAOAMAOB
SCHEMBL30656066 0.83 SCN9A (0.35) PPARDPPARAPPARGCD38OPRL1
SCHEMBL30656176 0.83 CD38 (0.36) PPARDPPARAEDNRACD38OPRL1
SCHEMBL30656016 0.83 CD38 (0.36) PPARDPPARAEDNRACD38OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed