SCHEMBL30656197

SCHEMBL30656197

Cc1sc2ccc(OCc3cccnc3C(F)(F)F)cc2c1C(=O)NCC(C)(C)O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.35
CD38 P28907 1/20 0.35
OPRL1 P41146 1/20 0.33
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33
CFTR P13569 1/20 0.33
ROCK2 O75116 2/20 0.33
CNR2 P34972 1/20 0.33
PTGFR P43088 4/20 0.32
PPARG P37231 1/20 0.32
SLC26A4 O43511 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
CD274 Q9NZQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656331 0.88 ALDH1A1 (0.38) CD38OPRL1PPARDPPARAPPARG
SCHEMBL30656076 0.87 ALDH1A1 (0.42) L3MBTL1
SCHEMBL30656093 0.86 ALOX5 (0.39) CD38L3MBTL1HTTCD274
SCHEMBL30655957 0.85 CD38 (0.38) CD38OPRL1PPARDPPARAROCK2
SCHEMBL30656120 0.85 SLC26A4 (0.42) CD38OPRL1PPARDPPARAPPARG
SCHEMBL31350334 0.85 CD38 (0.42) CD38OPRL1PPARDPPARAPPARG
SCHEMBL30656056 0.84 CD38 (0.37) SCN9ACD38OPRL1L3MBTL1MAPK1
SCHEMBL30656066 0.84 SCN9A (0.35) SCN9ACD38OPRL1PPARDPPARA
SCHEMBL30656258 0.83 CD38 (0.37) SCN9ACD38OPRL1L3MBTL1
SCHEMBL30656226 0.83 CD38 (0.37) SCN9ACD38OPRL1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed