SCHEMBL30656155

SCHEMBL30656155

CNC(=O)C1(NC(=O)c2c(C)sc3ccc(OCc4cnc(C)s4)cc23)CCOC1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CCNE1 P24864 1/20 0.32
CDK2 P24941 1/20 0.32
GSK3B P49841 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
ALOX5 P09917 1/20 0.30
ADAMTS4 O75173 1/20 0.30
MMP3 P08254 1/20 0.30
MMP7 P09237 1/20 0.30
ADAM17 P78536 1/20 0.30
ADAMTS1 Q9UHI8 1/20 0.30
ADAMTS5 Q9UNA0 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656261 0.91 CNR2 (0.34) CCNE1CDK2GSK3BCYP4F2CYP4A11
SCHEMBL30656207 0.88 CNR2 (0.38) CYP4F2CYP4A11L3MBTL1ALOX5ADAMTS4
SCHEMBL30656075 0.86 L3MBTL1 (0.32) L3MBTL1
SCHEMBL30656102 0.83 MMP3 (0.38) CCNE1CDK2GSK3BL3MBTL1ADAMTS4
SCHEMBL30656220 0.82 L3MBTL1 (0.33) L3MBTL1ADAMTS4MMP3MMP7ADAM17
SCHEMBL30656263 0.81 L3MBTL1 (0.34) L3MBTL1ADAMTS4MMP3MMP7ADAM17
SCHEMBL30656104 0.80 ABL1 (0.36) L3MBTL1ADAM17
SCHEMBL24485426 0.77 GAA (0.42) L3MBTL1
SCHEMBL29629720 0.77 GAA (0.42) L3MBTL1
SCHEMBL24484860 0.76 KMT2A (0.42) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed