SCHEMBL30656256

SCHEMBL30656256

Cc1sc2ccc(OCc3ccccc3)cc2c1C(=O)NCCN1CCOC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.44
FAAH O00519 1/20 0.43
MAPT P10636 4/20 0.42
LMNA P02545 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
EDNRA P25101 1/20 0.41
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KMT2A Q03164 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAOB P27338 3/20 0.40
MAOA P21397 2/20 0.40
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656114 0.88 NAAA (0.44) NAAAFAAHMAPTLMNAKDM4E
SCHEMBL30656271 0.85 SCN9A (0.38) MAPTLMNAKDM4EHPGDALDH1A1
SCHEMBL30656287 0.83 SCN9A (0.41) MAPTLMNAKDM4EALDH1A1POLB
SCHEMBL31350354 0.82 ALDH1A1 (0.42) NAAAFAAHMAPTLMNAEDNRA
SCHEMBL30714710 0.80 NAAA (0.44) NAAAFAAHMAPTLMNAKDM4E
SCHEMBL30656086 0.79 ALOX5 (0.55) MAPTLMNAKDM4EHTTEDNRA
SCHEMBL30656138 0.78 KDM4E (0.47) MAPTLMNAKDM4EHPGDHTT
SCHEMBL26793496 0.78 SLC6A5 (0.49) LMNAKDM4EEDNRAALDH1A1KMT2A
SCHEMBL30656021 0.77 EDNRA (0.53) MAPTKDM4EEDNRAALDH1A1KMT2A
SCHEMBL30656320 0.77 SLC6A5 (0.49) LMNAKDM4EEDNRAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed