Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569710 | 0.71 | KMT2A (0.49) | ALDH1A1POLBRAB9AHPGDTDP1 | |
| SCHEMBL15569708 | 0.71 | KMT2A (0.49) | ALDH1A1POLBRAB9AHPGDTDP1 | |
| SCHEMBL6891792 | 0.71 | ALDH1A1 (0.62) | ALDH1A1POLBRAB9AGAAHPGD | |
| SCHEMBL12006023 | 0.71 | RAB9A (0.46) | ALDH1A1POLBRAB9AGAAHPGD | |
| SCHEMBL2496089 | 0.70 | TDP1 (0.67) | ALDH1A1RAB9AHPGDKDM4EG6PD | |
| SCHEMBL7329105 | 0.69 | TSHR (0.44) | ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL3065600 | 0.69 | ADRA2B (0.48) | — | |
| SCHEMBL10773281 | 0.69 | ALDH1A1 (0.58) | ALDH1A1POLBGAATDP1MAPT | |
| SCHEMBL10774201 | 0.68 | ALDH1A1 (0.42) | ALDH1A1POLBRAB9AGAATDP1 | |
| SCHEMBL10677188 | 0.68 | ALDH1A1 (0.48) | ALDH1A1POLBRAB9AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267795-A1 | NITROSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-21 | — | — | US | disclosed |
| US-20100267795-A1 | NITROSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-21 | — | — | US | disclosed |
| EP-2217066-A1 | NITROSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | Syngenta Participations AG (CH) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009060173-A1 | NITROSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009060173-A1 | NITROSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267795-A1 | NITROSUBSTITUTED ARYLOXYALKYLIMIDAZOLINES FOR USE AS PESTICIDES | NISCH, DDT, CBR3 | ALDH1A1 1322/4885POLB 4701/4885RAB9A 1339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.