Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.42 |
| ▸ | MAP3K12 | Q12852 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 6/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639939 | 0.86 | QDPR (0.38) | QDPRACHEBACE1PIK3CDPIK3CA | |
| SCHEMBL26639913 | 0.82 | HTR1A (0.30) | — | |
| SCHEMBL26639880 | 0.74 | SOS1 (0.62) | — | |
| SCHEMBL26639760 | 0.67 | MEN1 (0.34) | — | |
| SCHEMBL30657478 | 0.67 | MEN1 (0.34) | — | |
| SCHEMBL30657485 | 0.67 | MEN1 (0.34) | — | |
| SCHEMBL26639820 | 0.67 | MEN1 (0.34) | — | |
| SCHEMBL30657462 | 0.67 | HRH4 (0.41) | ACHEBACE1 | |
| SCHEMBL26639919 | 0.67 | HRH4 (0.41) | ACHEBACE1 | |
| SCHEMBL12184261 | 0.67 | QDPR (0.44) | QDPRMAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215256-A1 | SOS1 INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |