Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078742 | 0.83 | ADORA2A (0.39) | ALDH1A1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3657811 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3081832 | 0.79 | KDM4E (0.44) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL1694984 | 0.71 | RAB9A (0.62) | ALDH1A1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5785695 | 0.71 | MTNR1A (0.43) | ALDH1A1HPGDEGLN1MTNR1ARAB9A | |
| SCHEMBL3794949 | 0.71 | CHRM2 (0.36) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28214523 | 0.71 | MTNR1A (0.41) | ALDH1A1MTNR1AKMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL3089379 | 0.70 | SSTR4 (0.33) | KMT2ASMN1; SMN2P2RX7 | |
| Hydrochloric Acid SCHEMBL7603529 | 0.70 | RAB9A (0.61) | ALDH1A1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11341145 | 0.70 | PSMD14 (0.41) | ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | ALDH1A1 2468/4885HPGD 3368/4885EGLN1 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.