Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14895794 | 0.78 | CYP4F2 (0.50) | MTNR1AMTNR1BL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL22552003 | 0.75 | KMT2A (0.47) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL19444397 | 0.74 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL27939662 | 0.74 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18995127 | 0.73 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2CYP2C19 | |
| SCHEMBL23633151 | 0.73 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL13732992 | 0.72 | HDAC3 (0.49) | MTNR1AMTNR1BL3MBTL1KMT2ACYP2D6 | |
| SCHEMBL2843465 | 0.72 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2CYP2C19POLB | |
| SCHEMBL11198582 | 0.72 | LIPG (0.49) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL16965688 | 0.71 | MPO (0.59) | ALDH1A1L3MBTL1KMT2ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570683-B | Polysubstituted aminated compounds and its preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |