Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 10/20 | 0.40 |
| ▸ | JAK3 | P52333 | 8/20 | 0.40 |
| ▸ | TYK2 | P29597 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 9/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | STAT3 | P40763 | 3/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | PAK4 | O96013 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929573 | 0.84 | TBK1 (0.42) | TBK1ALKCDK19JAK1JAK3 | |
| SCHEMBL27240978 | 0.84 | TBK1 (0.42) | TBK1ALKCDK19JAK1JAK3 | |
| SCHEMBL26979795 | 0.82 | JAK3 (0.49) | JAK1JAK3JAK2 | |
| SCHEMBL29928848 | 0.80 | CCNT1 (0.42) | TBK1JAK1JAK3TYK2KDR | |
| SCHEMBL27241032 | 0.80 | CCNT1 (0.42) | TBK1JAK1JAK3TYK2KDR | |
| SCHEMBL29113541 | 0.75 | JAK3 (0.40) | JAK1JAK3TYK2AURKBJAK2 | |
| SCHEMBL29113546 | 0.74 | LRRK2 (0.39) | JAK1JAK3TYK2KDRJAK2 | |
| SCHEMBL29113535 | 0.74 | LRRK2 (0.40) | JAK1JAK3KDRJAK2SYK | |
| SCHEMBL30671851 | 0.73 | JAK2 (0.49) | JAK3JAK2CDK2SYK | |
| SCHEMBL29113559 | 0.73 | JAK2 (0.49) | JAK3JAK2CDK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136184-A | Aminopyrimidine compounds and methods of use thereof | 泰拉生物科学公司 | 2023-11-28 | — | — | CN | disclosed |