SCHEMBL3067924

SCHEMBL3067924

c1ccc2c(c1)ncn2COCn1cnc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.68
SMN1; SMN2 Q16637 6/20 0.66
LMNA P02545 5/20 0.66
CYP11B1 P15538 6/20 0.59
CYP11B2 P19099 6/20 0.59
TNF P01375 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.57
HTT P42858 3/20 0.56
MAPK1 P28482 1/20 0.54
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
EGLN3 Q9H6Z9 1/20 0.53
RAB9A P51151 2/20 0.51
GAA P10253 1/20 0.51
NPC1 O15118 1/20 0.50
MAPT P10636 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9670554 0.89 TDP1 (0.59) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL1623128 0.86 AGER (0.64) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL2640498 0.85 TDP1 (0.63) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL2357255 0.84 SMN1; SMN2 (0.56) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL30013328 0.84 SMN1; SMN2 (0.56) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL15554099 0.84 LMNA (0.55) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL15068565 0.83 L3MBTL1 (0.71) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL30564238 0.81 TDP1 (0.76) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL6442808 0.81 TDP1 (1.00) TDP1SMN1; SMN2LMNACYP11B1CYP11B2
SCHEMBL6794361 0.81 TDP1 (0.76) TDP1SMN1; SMN2LMNACYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
US-7407711-B2 Non-toxic corrosion-protection conversion coats based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-08-05 US disclosed
US-7294211-B2 Non-toxic corrosion-protection conversion coats based on cobalt UNIVERSITY OF DAYTON (US) 2007-11-13 US disclosed
US-7291217-B2 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON (US) 2007-11-06 US disclosed
US-20070149673-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE STURGILL JEFFREY A 2007-06-28 US disclosed
US-7235142-B2 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON (US) 2007-06-26 US disclosed
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed