Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.34 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20744369 | 1.00 | MAP4K4 (0.41) | MAP4K4MTORAAK1CYP1A2POLB | |
| SCHEMBL28439392 | 0.85 | CSNK1D (0.33) | MTORHRH4NLRP3CSNK1DCSNK1E | |
| SCHEMBL20744447 | 0.83 | DYRK1A (0.39) | AAK1HRH4NLRP3MAPK13MAPK12 | |
| SCHEMBL29573583 | 0.83 | ADORA2B (0.43) | MAP4K4AAK1HRH4NLRP3MAPK13 | |
| SCHEMBL23012692 | 0.83 | ADORA2B (0.43) | MAP4K4AAK1HRH4NLRP3MAPK13 | |
| SCHEMBL20744375 | 0.83 | NLRP3 (0.41) | AAK1HRH4NLRP3MAPK13MAPK12 | |
| SCHEMBL30684077 | 0.83 | NLRP3 (0.41) | AAK1HRH4NLRP3MAPK13MAPK12 | |
| SCHEMBL20743706 | 0.82 | TDO2 (0.39) | MAP4K4MTORAAK1HRH4TDO2 | |
| SCHEMBL30684113 | 0.82 | TDO2 (0.39) | MAP4K4MTORAAK1HRH4TDO2 | |
| SCHEMBL20744379 | 0.81 | ALOX5AP (0.36) | HRH4NLRP3MAPK14ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132974-B | Sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2023-11-21 | — | — | CN | disclosed |