Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22281011 | 1.00 | F9 (0.39) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL22264899 | 0.84 | KMT2A (0.42) | ALDH1A1L3MBTL1GAATSHRSMN1; SMN2 | |
| SCHEMBL22264897 | 0.84 | KMT2A (0.42) | ALDH1A1L3MBTL1GAATSHRSMN1; SMN2 | |
| SCHEMBL28463373 | 0.83 | MAPT (0.38) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL28457435 | 0.83 | MAPT (0.38) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL28457438 | 0.83 | MAPT (0.38) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL29091950 | 0.82 | ALDH1A1 (0.42) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL27235800 | 0.82 | ALDH1A1 (0.42) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL29530222 | 0.82 | ALDH1A1 (0.42) | F9PLAUALDH1A1L3MBTL1ALDH2 | |
| SCHEMBL21167054 | 0.77 | LMNA (0.35) | ALDH1A1SMN1; SMN2MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914256-B1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES INC (US) | 2024-05-29 | — | — | EP | disclosed |
| US-11773101-B2 | GPR35 modulators | PROMETHEUS BIOSCIENCES, INC. (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773101-B2 | GPR35 modulators | GPR35, GPR55, GPR65 | F9 4883/4885PLAU 3416/4885ALDH1A1 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.