SCHEMBL30693102

SCHEMBL30693102

Ic1c(I)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
ALDH1A1 P00352 3/20 0.47
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
EGFR P00533 1/20 0.41
MAPK1 P28482 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PLA2G10 O15496 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
ACHE P22303 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18904960 0.94 LMNA (0.48) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL598477 0.90 ALDH1A1 (0.50) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL26907979 0.83 PDE4B (0.39) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL216526 0.83 ALDH1A1 (0.67) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL22717148 0.82 ESR1 (0.48) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL5637259 0.79 ALDH1A1 (0.61) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL20081033 0.79 LMNA (0.46) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL22717278 0.78 LMNA (0.40) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL28556066 0.76 PDE4B (0.42) LMNAMAPTHTTALDH1A1ESR1
SCHEMBL5949483 0.76 ALDH1A1 (0.69) LMNAMAPTHTTALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071990-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS SemiconBio Inc. (US) 2026-03-12 US disclosed
US-12504396-B2 Polycyclic aromatic bridges for molecular electronic sensors SemiconBio (US) 2025-12-23 US disclosed
US-20250085251-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS Roswell Biotechnologies, Inc. (US) 2025-03-13 US disclosed
EP-3953491-B1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS ROSWELL BIOTECHNOLOGIES INC (US) 2023-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250085251-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS ALK, GJB2, ALKBH3 LMNA 979/4885MAPT 3034/4885HTT 3615/4885
US-20260071990-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS GJB2, STIM2, SMC3 LMNA 1391/4885MAPT 4150/4885HTT 4620/4885
US-12504396-B2 Polycyclic aromatic bridges for molecular electronic sensors ALK, GJB2, ALKBH3 LMNA 979/4885MAPT 3034/4885HTT 3615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.