Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | SORD | Q00796 | 4/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27457779 | 0.83 | ROCK2 (0.44) | PTGER4SORDROCK2HRH3GSK3A | |
| SCHEMBL21880062 | 0.83 | KMO (0.53) | SORDKMOHRH3HRH4PIK3CA | |
| SCHEMBL31705707 | 0.80 | SORD (0.42) | PTGER4SORDKMOHRH3HRH4 | |
| SCHEMBL27457591 | 0.77 | GBA1 (0.47) | PTGER4 | |
| SCHEMBL22122190 | 0.77 | PIK3CA (0.65) | PTGER4GSK3BPIK3CA | |
| SCHEMBL31705670 | 0.76 | MAP4K4 (0.52) | SORD | |
| SCHEMBL30954009 | 0.75 | TRPV1 (0.47) | SORDHRH3HRH4 | |
| SCHEMBL30693986 | 0.75 | HRH3 (0.43) | PTGER4SORDROCK2HRH3ACACB | |
| SCHEMBL30954035 | 0.75 | HRH3 (0.66) | SORDROCK2HRH3GSK3AGSK3B | |
| SCHEMBL26618088 | 0.75 | TRPV1 (0.47) | SORDHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137984-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024137984-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |