SCHEMBL30697180

SCHEMBL30697180

Fc1ccccc1F.N=C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.42
CES1 P23141 3/20 0.42
ACHE P22303 1/20 0.41
NFE2L2 Q16236 1/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
NPC1 O15118 2/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MGLL Q99685 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
GAA P10253 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33
BCHE P06276 1/20 0.33
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
PSIP1 O75475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27904908 1.00 CES2 (0.42) CES2CES1ACHENFE2L2ALDH1A1
SCHEMBL3545494 0.82 CES2 (0.46) CES2CES1ACHEBCHEHPGD
SCHEMBL27692834 0.82 LMNA (0.41) CES2CES1NFE2L2ALDH1A1ALOX15
SCHEMBL28277174 0.82 ACHE (0.71) CES2CES1ACHEALDH1A1NPC1
SCHEMBL28983293 0.82 ACHE (0.71) CES2CES1ACHEALDH1A1NPC1
Isothiocyanate SCHEMBL27717579 0.81 ACHE (0.41) CES2CES1ACHENFE2L2ALDH1A1
SCHEMBL45406 0.79
SCHEMBL29352330 0.79
Fluorobenzene SCHEMBL9630082 0.79 NFE2L2 (0.40) CES2CES1NFE2L2ALDH1A1NPC1
Fluorobenzene SCHEMBL20558451 0.79 NFE2L2 (0.40) CES2CES1NFE2L2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746696-B Polyimide paint for high-heat-resistance enameled wire and high-heat-resistance enameled wire 浙江中科玖源新材料有限公司 2023-12-19 CN claimed
CN-118638407-A Modified nylon material for laser welding and preparation method thereof 瑞安市君诚塑胶制造有限公司 2024-09-13 CN disclosed
CN-114380874-B Macrolide antibiotics, preparation method and application thereof 中国医学科学院医药生物技术研究所 2024-06-21 CN disclosed
CN-115746696-B Polyimide paint for high-heat-resistance enameled wire and high-heat-resistance enameled wire 浙江中科玖源新材料有限公司 2023-12-19 CN disclosed