Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 6/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 5/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700401 | 0.90 | GPR119 (0.40) | FAAHMGLLGPR119KCNH2 | |
| SCHEMBL30700437 | 0.88 | MGLL (0.40) | FAAHMGLLGPR119RORC | |
| SCHEMBL30700301 | 0.87 | MGLL (0.44) | FAAHMGLL | |
| SCHEMBL30699904 | 0.79 | MGLL (0.37) | FAAHMGLLGPR119KCNH2RORC | |
| SCHEMBL25326394 | 0.78 | MGLL (0.36) | FAAHMGLLGPR119KCNH2RORC | |
| SCHEMBL30700127 | 0.78 | MGLL (0.42) | FAAHMGLL | |
| SCHEMBL30700338 | 0.76 | GPR119 (0.41) | FAAHGPR119KCNH2 | |
| SCHEMBL30700368 | 0.75 | MGLL (0.40) | FAAHMGLL | |
| SCHEMBL30700053 | 0.74 | MGLL (0.40) | FAAHMGLL | |
| SCHEMBL30700344 | 0.74 | GPR119 (0.41) | FAAHGPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |