Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700192 | 0.90 | FAAH (0.36) | GPR119FAAHKCNH2MGLL | |
| SCHEMBL30700338 | 0.85 | GPR119 (0.41) | GPR119FAAHKCNH2CYP3A4 | |
| SCHEMBL30700301 | 0.85 | MGLL (0.44) | FAAHMGLL | |
| SCHEMBL30700344 | 0.84 | GPR119 (0.41) | GPR119FAAHKCNH2CYP3A4 | |
| SCHEMBL30700327 | 0.82 | GPR119 (0.34) | GPR119KCNH2MGLL | |
| SCHEMBL30699892 | 0.81 | GPR119 (0.42) | GPR119KCNH2 | |
| SCHEMBL30700355 | 0.79 | GPR119 (0.42) | GPR119FAAHKCNH2AOC3CYP3A4 | |
| SCHEMBL30700437 | 0.79 | MGLL (0.40) | GPR119FAAHMGLL | |
| SCHEMBL30700421 | 0.78 | GPR119 (0.40) | GPR119KCNH2CYP3A4 | |
| SCHEMBL25325310 | 0.77 | GPR119 (0.38) | GPR119FAAHKCNH2CYP3A4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |