Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700192 | 0.88 | FAAH (0.36) | MGLLFAAHGPR119RORC | |
| SCHEMBL30700127 | 0.86 | MGLL (0.42) | MGLLFAAHJAK2JAK1PIK3CD | |
| SCHEMBL30700368 | 0.81 | MGLL (0.40) | MGLLFAAHPIK3CDPIK3R1 | |
| SCHEMBL30700110 | 0.81 | ENPP2 (0.39) | MGLLJAK2JAK1PIK3CDPIK3R1 | |
| SCHEMBL30700053 | 0.79 | MGLL (0.40) | MGLLFAAHPIK3CDLIPG | |
| SCHEMBL30700401 | 0.79 | GPR119 (0.40) | MGLLFAAHGPR119 | |
| SCHEMBL30700668 | 0.78 | MGLL (0.36) | MGLLLMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL30700770 | 0.78 | MGLL (0.42) | MGLLFAAHTEAD1SCN3APTPRZ1 | |
| SCHEMBL30700301 | 0.77 | MGLL (0.44) | MGLLFAAHJAK2JAK1LIPG | |
| SCHEMBL25324021 | 0.76 | MGLL (0.38) | MGLLFAAHTEAD1SCN3APTPRZ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |