Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 19/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700117 | 0.89 | DPP4 (0.40) | CCNKCDK12HCRTR1 | |
| SCHEMBL30700784 | 0.85 | GPR119 (0.37) | HCRTR1HCRTR2 | |
| SCHEMBL30700068 | 0.84 | HCRTR1 (0.33) | CCNKCDK12HCRTR1HCRTR2 | |
| SCHEMBL30700282 | 0.81 | ENPP2 (0.38) | — | |
| SCHEMBL30700041 | 0.81 | CCNK (0.44) | CCNKCDK12HCRTR1 | |
| SCHEMBL30699937 | 0.81 | CCNK (0.44) | CCNKCDK12HCRTR1 | |
| SCHEMBL25324903 | 0.80 | CCNK (0.38) | CCNKCDK12HCRTR1 | |
| SCHEMBL30553201 | 0.80 | CCNK (0.38) | CCNKCDK12HCRTR1 | |
| SCHEMBL30700375 | 0.78 | LOXL2 (0.36) | — | |
| SCHEMBL30699966 | 0.77 | LOXL2 (0.33) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |