Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700375 | 0.88 | LOXL2 (0.36) | GPR119LOXL2MDM2 | |
| SCHEMBL30699966 | 0.88 | LOXL2 (0.33) | GPR119HCRTR1LOXL2HCRTR2 | |
| SCHEMBL30700477 | 0.85 | CCNK (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL30700206 | 0.84 | MALT1 (0.35) | GPR119LOXL2MDM2 | |
| SCHEMBL30700068 | 0.83 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL30700138 | 0.81 | GPR119 (0.36) | GPR119HCRTR1LOXL2HCRTR2 | |
| SCHEMBL30700595 | 0.80 | GPR119 (0.37) | GPR119HCRTR1LOXL2HCRTR2LIPE | |
| SCHEMBL30700450 | 0.80 | GPR119 (0.38) | GPR119HCRTR1LOXL2LIPE | |
| SCHEMBL30700282 | 0.80 | ENPP2 (0.38) | — | |
| SCHEMBL25326437 | 0.79 | GPR119 (0.35) | GPR119HCRTR1LOXL2HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |