Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 4/20 | 0.45 |
| ▸ | KDM8 | Q8N371 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769843 | 0.85 | KDM4E (0.43) | ASPHKDM8KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL31072272 | 0.85 | KDM4E (0.43) | ASPHKDM8KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL31208501 | 0.81 | OPRK1 (0.42) | PDK2PDK4SLC6A3OPRK1 | |
| SCHEMBL9319224 | 0.78 | KDM4E (0.53) | ASPHKDM8KDM4EMAPK1L3MBTL1 | |
| SCHEMBL24660110 | 0.77 | ASPH (0.40) | ASPHKDM8KDM4EMAPK1L3MBTL1 | |
| SCHEMBL31318735 | 0.75 | KDM4E (0.50) | ASPHKDM8KDM4EMAPK1L3MBTL1 | |
| SCHEMBL29878040 | 0.75 | MAPK1 (0.41) | KDM4EMAPK1CNR2LMNASLC6A3 | |
| SCHEMBL21616744 | 0.74 | ASPH (0.45) | ASPHKDM8KDM4EL3MBTL1RIOX2 | |
| SCHEMBL21623504 | 0.73 | GABRA1 (0.41) | KDM4EMAPK1L3MBTL1PDK2PDK4 | |
| SCHEMBL29695156 | 0.73 | OPRK1 (0.43) | KDM4EPDK2PDK4CNR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113348170-B | Biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |