Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769843 | 1.00 | KDM4E (0.43) | KDM4EHSD17B10ASPHKDM8CSNK1D | |
| SCHEMBL30703822 | 0.85 | ASPH (0.45) | KDM4EASPHKDM8SMN1; SMN2LMNA | |
| SCHEMBL31208517 | 0.82 | IGF1R (0.43) | KDM4EHSD17B10CSNK1DCYP2C19FOS | |
| SCHEMBL9318633 | 0.80 | KDM4E (0.49) | KDM4EASPHKDM8CYP2C9CYP2C19 | |
| SCHEMBL29391322 | 0.79 | TSHR (0.50) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL22675456 | 0.79 | RAB9A (0.41) | KDM4EHSD17B10CSNK1DCYP2C19FOS | |
| SCHEMBL22769846 | 0.77 | PDCD1 (0.68) | PDCD1CD274 | |
| SCHEMBL26616033 | 0.75 | FOS (0.39) | KDM4EHSD17B10CSNK1DCYP2C9CYP2C19 | |
| SCHEMBL31440845 | 0.75 | FOS (0.39) | KDM4EHSD17B10CSNK1DCYP2C9CYP2C19 | |
| SCHEMBL22675639 | 0.75 | ALDH1A1 (0.44) | KDM4EHSD17B10CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448189-B | Biaryl derivative, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-09-10 | — | — | CN | disclosed |