Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29606152 | 0.82 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL24397879 | 0.81 | CRHR1 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2CYP3A4CRHR1 | |
| SCHEMBL29606169 | 0.79 | LMNA (0.36) | ALDH1A1L3MBTL1LMNAPOLBPTPN7 | |
| SCHEMBL28456810 | 0.77 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL29606778 | 0.77 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL29606642 | 0.74 | CYP3A4 (0.42) | ALDH1A1L3MBTL1LMNAPOLBCYP3A4 | |
| SCHEMBL28455365 | 0.74 | CYP3A4 (0.42) | ALDH1A1L3MBTL1LMNAPOLBCYP3A4 | |
| SCHEMBL28794509 | 0.73 | AKR1C4 (0.55) | ALDH1A1SMN1; SMN2CYP3A4GAAHPGD | |
| SCHEMBL24397792 | 0.70 | LMNA (0.54) | ALDH1A1L3MBTL1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL29129851 | 0.69 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |