SCHEMBL30705228

SCHEMBL30705228

O=C(O)c1ccc(Oc2ccc(-c3cccc(Oc4ccc(C(=O)O)cc4)c3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.67
RXRB P28702 4/20 0.67
SRD5A2 P31213 3/20 0.61
AKR1C3 P42330 1/20 0.61
FFAR4 Q5NUL3 2/20 0.58
FFAR1 O14842 1/20 0.58
PTGES O14684 1/20 0.56
ALOX5 P09917 1/20 0.56
TRIM24 O15164 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
PARP15 Q460N3 1/20 0.53
PARP10 Q53GL7 1/20 0.53
RXRG P48443 1/20 0.53
BCL2 P10415 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5038677 1.00 RXRA (0.67) RXRARXRBSRD5A2AKR1C3FFAR4
SCHEMBL29963803 0.96 SRD5A2 (0.65) RXRARXRBSRD5A2AKR1C3FFAR4
SCHEMBL5042492 0.96 SRD5A2 (0.65) RXRARXRBSRD5A2AKR1C3FFAR4
SCHEMBL5044252 0.92 AKR1C3 (0.74) RXRARXRBAKR1C3FFAR4FFAR1
SCHEMBL30705230 0.92 AKR1C3 (0.74) RXRARXRBAKR1C3FFAR4FFAR1
SCHEMBL2708209 0.87 SRD5A2 (0.71) RXRARXRBSRD5A2AKR1C3PARP15
SCHEMBL11419154 0.87 SRD5A2 (0.71) RXRARXRBSRD5A2AKR1C3PTGES
SCHEMBL8999835 0.87 SRD5A2 (0.78) SRD5A2AKR1C3PARP15PARP10
SCHEMBL5038711 0.87 EGFR (0.55) RXRARXRBSRD5A2AKR1C3FFAR4
SCHEMBL2747020 0.86 AKR1C3 (0.82) SRD5A2AKR1C3LMNAGAAPARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112080026-B Polyimide film having voids and method for producing same 旭化成株式会社 2024-01-23 CN disclosed