Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS2 | Q07890 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659741 | 0.87 | SOS2 (0.39) | SOS2NQO1SRCCDC7EGLN2 | |
| SCHEMBL1994814 | 0.80 | ALDH1A1 (0.47) | SOS2NQO1SRC | |
| Hydrochloric Acid SCHEMBL27619885 | 0.79 | ALDH1A1 (0.46) | SOS2NQO1SRC | |
| SCHEMBL5346454 | 0.78 | SOS2 (0.63) | SOS2NQO1SRCCDC7CTSB | |
| SCHEMBL14629289 | 0.76 | MAPT (0.48) | SOS2NQO1SRCCTSBCTSK | |
| SCHEMBL31317257 | 0.75 | NQO1 (0.40) | SOS2NQO1SRCCTSBHPGDS | |
| SCHEMBL5583902 | 0.74 | CYP11B1 (0.37) | SOS2NQO1CDC7HPGDSCCNC | |
| SCHEMBL19779353 | 0.72 | SOS2 (0.39) | SOS2NQO1SRC | |
| SCHEMBL29712713 | 0.72 | NQO1 (0.41) | SOS2NQO1CTSKHPGDSLTA4H | |
| SCHEMBL995983 | 0.71 | SOS2 (0.50) | SOS2NQO1SRCCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11866430-B2 | Naphthyridinone compounds useful as T cell activators | DGKZ, DGKA, DGKG | SOS2 4088/4885NQO1 1466/4885SRC 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.