Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26986818 | 1.00 | GAA (0.65) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL26986059 | 0.95 | GAA (0.71) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL432419 | 0.82 | ALDH1A1 (0.68) | MAPK1LMNAMAPTPOLBTSHR | |
| SCHEMBL26986392 | 0.81 | GAA (0.71) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL13175539 | 0.81 | RAB9A (0.68) | LMNAPOLBTSHRKMT2AALDH1A1 | |
| SCHEMBL30706456 | 0.81 | GAA (0.67) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL27131671 | 0.81 | GAA (0.67) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL26986179 | 0.80 | GAA (1.00) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL31531882 | 0.78 | GAA (0.74) | GAAMAPK1LMNAMAPTPOLB | |
| SCHEMBL26986301 | 0.78 | GAA (0.74) | GAAMAPK1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352542-A1 | TRPV2 CHANNEL BLOCKERS AND USE THEREOF | ICHILOV TECH LTD. (IL) | 2025-11-20 | — | — | US | disclosed |
| EP-4551568-A1 | TRPV2 CHANNEL BLOCKERS AND USE THEREOF | Ichilov Tech Ltd. (IL) | 2025-05-14 | — | — | EP | disclosed |
| CN-119816492-A | TRPV2 channel blocker and use thereof | 伊契洛夫科技有限公司 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024009308-A1 | TRPV2 CHANNEL BLOCKERS AND USE THEREOF | ICHILOV TECH LTD. (IL) | 2024-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250352542-A1 | TRPV2 CHANNEL BLOCKERS AND USE THEREOF | TRPV2, TRPV1, TRPA1 | GAA 3374/4885MAPK1 2680/4885LMNA 2676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.