Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | DDX3X | O00571 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175539 | 0.98 | RAB9A (0.68) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL3647856 | 0.86 | KDM4E (0.68) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL12694399 | 0.86 | NPC1 (0.68) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL913960 | 0.84 | DDX3X (0.59) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL30706459 | 0.82 | GAA (0.65) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL26986818 | 0.82 | GAA (0.65) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL13074676 | 0.81 | LMNA (0.56) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL28336995 | 0.81 | POLB (0.75) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL11641875 | 0.81 | NPSR1 (1.00) | ALDH1A1MEN1KMT2ARECQLNPSR1 | |
| SCHEMBL12082422 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ARECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834645-B | Epoxy adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-118834645-A | Epoxy adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2024-10-25 | — | — | CN | claimed |
| EP-4656249-A2 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | Daewoong Pharmaceutical Co., Ltd. (KR) | 2025-12-03 | — | — | EP | disclosed |
| CN-118834645-B | Epoxy adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118834645-A | Epoxy adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-3478687-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | DAEWOONG PHARMACEUTICAL CO LTD (KR) | 2024-03-20 | — | — | EP | disclosed |
| EP-3950691-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | Daewoong Pharmaceutical Co., Ltd. (KR) | 2022-02-09 | — | — | EP | disclosed |
| CN-109311896-B | Pyrazolopyrimidine derivatives as kinase inhibitors | 株式会社大熊制药 | 2021-08-24 | — | — | CN | disclosed |
| CN-113135920-A | Pyrazolopyrimidine derivatives as kinase inhibitors | 株式会社大熊制药 | 2021-07-20 | — | — | CN | disclosed |
| US-10961247-B2 | Pyrazolopyrimidine derivatives as kinase inhibitor | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-03-30 | — | — | US | disclosed |
| US-20200317673-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-10-08 | — | — | US | disclosed |
| US-20110005947-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| WO-2010129802-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100056524-A1 | Compound | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-03-04 | — | — | US | disclosed |
| US-20100056524-A1 | Compound | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-03-04 | — | — | US | disclosed |
| WO-2009122180-A1 | PYRIMIDINE DERIVATIVES CAPABLE OF INHIBITING ONE OR MORE KINASES | MEDICAL RESEARCH COUNCIL (GB) | 2009-10-08 | — | — | WO | disclosed |
| US-20090203673-A1 | 4-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| US-7504410-B2 | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-03-17 | — | — | US | disclosed |
| CN-1717396-A | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | SCHERING AG (DE) | 2006-01-04 | — | — | CN | disclosed |
| US-20040186118-A1 | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317673-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | MAP3K5, MAP3K2, MAPKAPK5 | ALDH1A1 1963/4885MEN1 3215/4885KMT2A 1427/4885 |
| US-20100056524-A1 | Compound | NR3C2, NR3C1, NR2E3 | ALDH1A1 2440/4885MEN1 3297/4885KMT2A 3200/4885 |
| US-20040186118-A1 | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | DCK, PDPK1, DTYMK | ALDH1A1 2532/4885MEN1 4334/4885KMT2A 2772/4885 |
| US-20110005947-A1 | INHIBITORS OF JAK | JAK1, JAK2, JAK3 | ALDH1A1 2512/4885MEN1 2502/4885KMT2A 1528/4885 |
| US-20090203673-A1 | 4-HETEROCYCLOALKYLPYRI(MI)DINES, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | CCNI, MKI67, CCNA1 | ALDH1A1 293/4885MEN1 143/4885KMT2A 3344/4885 |
| US-10961247-B2 | Pyrazolopyrimidine derivatives as kinase inhibitor | MAP3K5, MAP3K2, MAPKAPK5 | ALDH1A1 1963/4885MEN1 3215/4885KMT2A 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.