Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | AKT2 | P31751 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.37 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2572859 | 0.94 | PLAU (0.43) | PLAUBACE1AKT2PLGPLAT | |
| Trifluoroacetic Acid SCHEMBL2572861 | 0.94 | PLAU (0.43) | PLAUBACE1AKT2PLGPLAT | |
| SCHEMBL30708652 | 0.92 | CFD (0.40) | PLAUBACE1AKT2MEN1KMT2A | |
| SCHEMBL3157774 | 0.90 | PLAU (0.46) | PLAUBACE1AKT2CASP3MEN1 | |
| SCHEMBL3157766 | 0.90 | PLAU (0.46) | PLAUBACE1AKT2CASP3MEN1 | |
| SCHEMBL2571726 | 0.90 | LOXL2 (0.46) | PLAUBACE1PLATKLKB1MEN1 | |
| SCHEMBL2571723 | 0.90 | LOXL2 (0.46) | PLAUBACE1PLATKLKB1MEN1 | |
| SCHEMBL30708636 | 0.90 | BACE1 (0.41) | PLAUBACE1CASP3ROCK2RXFP1 | |
| SCHEMBL2570438 | 0.89 | BACE1 (0.46) | PLAUBACE1AKT2CASP3MEN1 | |
| SCHEMBL2570441 | 0.89 | BACE1 (0.46) | PLAUBACE1AKT2CASP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | MMP1, COL1A1, SMAD3 | PLAU 1160/4885BACE1 3038/4885AKT2 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.