Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2567046 | 0.94 | TPSAB1 (0.38) | CFDAKT2MEN1KMT2APLAU | |
| Trifluoroacetic Acid SCHEMBL2567048 | 0.94 | TPSAB1 (0.38) | CFDAKT2MEN1KMT2APLAU | |
| SCHEMBL2571324 | 0.92 | NPC1 (0.41) | AKT2MEN1KMT2APLAUPARP1 | |
| SCHEMBL2571321 | 0.92 | NPC1 (0.41) | AKT2MEN1KMT2APLAUPARP1 | |
| SCHEMBL30708643 | 0.92 | PLAU (0.47) | AKT2MEN1KMT2APLAUBACE1 | |
| SCHEMBL30708638 | 0.90 | KMT2A (0.37) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL30708629 | 0.89 | ROCK2 (0.38) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL16685264 | 0.88 | ROCK2 (0.46) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL16685268 | 0.88 | ROCK2 (0.46) | MEN1KMT2APARP1PARP15PARP10 | |
| SCHEMBL16685266 | 0.88 | ROCK2 (0.46) | MEN1KMT2APARP1PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372297-A1 | MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES | MMP1, COL1A1, SMAD3 | CFD 3232/4885AKT2 3227/4885MEN1 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.