SCHEMBL30709352

SCHEMBL30709352

c1ccc(-c2cccc(-c3ccccc3-c3c(-n4c5ccccc5c5cnccc54)c(-n4c5ccccc5c5cnccc54)nc(-n4c5ccccc5c5cnccc54)c3-n3c4ccccc4c4cnccc43)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.39
MAOA P21397 4/20 0.36
MAOB P27338 4/20 0.36
ACHE P22303 1/20 0.36
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
ALOX5 P09917 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK14 Q16539 1/20 0.32
CDC7 O00311 1/20 0.32
CDK2 P24941 1/20 0.32
DUSP3 P51452 1/20 0.32
ATM Q13315 1/20 0.31
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30709653 0.94 TNF (0.36) TNFMEN1RAB9AKMT2AALOX5
SCHEMBL30709495 0.91 KMT2A (0.42) MEN1RAB9AKMT2AMAPK14DUSP3
SCHEMBL22148532 0.87 MAOA (0.35) TNFMAOAMAOBACHEMEN1
SCHEMBL22148721 0.87 MAOA (0.35) TNFMAOAMAOBACHEMEN1
SCHEMBL22148660 0.87 MAOA (0.36) TNFMAOAMAOBACHEMEN1
SCHEMBL22148917 0.87 MAOA (0.36) TNFMAOAMAOBACHEMEN1
SCHEMBL30709206 0.87 MAOA (0.36) TNFMAOAMAOBACHEMEN1
SCHEMBL30709170 0.84 MAOA (0.38) TNFMAOAMAOBACHEMEN1
SCHEMBL22148542 0.84 MAOA (0.38) TNFMAOAMAOBACHEMEN1
SCHEMBL22148892 0.84 MAPK14 (0.41) TNFMAOAMAOBACHERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11849634-B2 Composition of matter for use in organic light- emitting diodes NDUFV3, NDUFV2, CRY2 TNF 3137/4885MAOA 120/4885MAOB 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.